What Does Wyf Mean?, This acronym stands for "Where You From?" Basically Usage: It is employed in casual conversations to ask about someone's location or their hometown. There are many occasions when you will see this acronym being utilized in text messages, social media, and online chatting. You could consider WYF as a great way of making an introduction, especially if you are connecting with new people online. Asking WYF shows interest in someone else's background and creates an engaging and friendly subject.